Neuro-lymphatics - how the brain clears waste
I’ve started offering a new type of bodywork this past fall that I’m calling neuro-lymphatic drainage. I’m incredibly excited about it, and think it’s going to be transformative for a lot of people. I also want to be clear about why I’m excited - there’s a lot of nonsense out there in the wellness world, and it can be hard to tell what’s for real.
When it comes to any kind of healing approach, I like to understand why it works. I want to know the anatomy being worked with, how it interacts with the rest of the body, and how the intervention works to create change. I acknowledge that very real results can come from interventions we don’t understand in this way, but I prefer to train in methods that I can explain scientifically.
So of course, when I first started learning about neuro-lymphatics, I was suspicious. Could it really be as powerful as it seems? How? Why?
Being the nerd that I am, I hit google scholar. Turns out, there’s lots of research backing it up. I just hadn’t heard about it before because it’s incredibly new stuff! In this blog post I want to share some of the key bits of research, and how I apply them to my practice.
Let’s start with the anatomy, since that’s what helps the rest of it make sense. I’ll try to keep the explanation in English instead of Medical, so I’ll stick to the parts that are relevant to what we’re talking about and simplify a lot of the technical terminology. Links to some of the articles I relied on writing this post are at the end if you want a deep dive.
The Glymphatic System
In the rest of the body, the waste products created by cells living their lives is cleared out by the lymphatic system - a one-way transportation system that moves excess fluid and anything collecting in it back towards the heart so it can drain into the bloodstream, get filtered by the liver and kidneys, and eventually get urinated out. The usual components of the lymphatic system aren’t found in the brain.
We didn’t know how the brain cleared its waste until new imaging techniques were developed and the “glymphatic system” was discovered in rodents in 2012. It’s called the glymphatic system because it works very similarly to how the lymphatic system works, and because the glial cells in the brain are part of the process. Even more recently in 2015, the meningeal lymphatics were identified as another part of the waste disposal route.
As we understand it now, the pathway of the brain’s metabolic waste and excess fluid is as follows:
the glymphatic system works with the meningeal lymphatic system to move it out of the brain
it exits through the base of the skull and behind the nose
it drains into the lymph nodes of the neck
the regular lymphatic system does its usual thing, cleaning it and carrying it towards the heart to join the bloodstream.
Neuro-lymphatic Drainage
When I talk about neuro-lymphatic drainage, I mean this waste disposal system that helps the brain function at its best, without too much toxic waste or accumulating fluid. When we can encourage the brain’s waste disposal, we help the brain work better.
In future posts, I’ll talk about what conditions we know are linked to problems with neuro-lymphatic drainage. I’ll also get into what we know can help maximize neuro-lymphatic drainage and what evidence there is for the hands-on techniques I use in therapy sessions. In the meantime, scroll down enjoy some anatomy and physiology science geekery!
A few recent articles on neuro-lymphatic anatomy and brain waste clearance:
Glymphatic system: an emerging therapeutic approach for neurological disorders - 2023
Glymphatic system: a gateway for neuroinflammation - 2023
Neurofluids and the glymphatic system: anatomy, physiology, and imaging - 2023
Non-invasive MR imaging of human brain lymphatic networks with connections to cervical lymph nodes - 2022
The glymphatic system and meningeal lymphatics of the brain: new understanding of brain clearance - 2021
Meningeal Lymphatics: A Review and Future Directions From a Clinical Perspective - 2019